![About the Pratt Lab
The overall theme of the lab is understanding the molecular consequences of posttranslational modifications (PTMs) including glycosylation and ubiquitination. These modifications expand the chemical diversity available to cells and living organisms. We specifically focus on the development of chemical tools as attractive methods for dissecting these biochemical pathways.
Currently we are applying these chemical approaches to reveal roles for PTMs in cellular responses is processes associated with changes in metabolism and stress. Recent evidence suggests that these pathways are important contributors to a variety of human diseases including neurodegeneration and cancer. To accomplish our scientific goals, members of the lab use combinations of organic synthesis, genetics, protein biochemistry, and cellular biology. Interested prospective graduate students should apply to the programs below, and postdoctoral candidates can email matthew.pratt[at]usc[dot]edu directly.](Home_files/shapeimage_2.png)
Matthew R. Pratt, Ph.D.
Assistant Professor
Departments of Chemistry and Molecular and Computational Biology
Member of the Norris Comprehensive Cancer Center
University of Southern California
840 Downey Way, LJS 250
Los Angeles, CA 90089-0744
phone: 213.740.3014
fax: 213.740.0930
email: matthew.pratt[at]usc[dot]edu
