A postdoctoral position is available immediately for a trained patch-clamp electrophysiologist to study mechanisms of regulation of TRP ion channels.  Research in the lab is aimed at understanding calcium regulation of TRP channels and the role of TRP channels in sensory processes, with an emphasis on TRPM5 (PNAS, 2003; JBC, 2005; J Neurosci. 2007), an ion channel that transduces taste, TRPM4 (JBC, 2005; JACS, 2006) and TRPA1, an ion channel involved in pain sensation (Biophysical Society abstract: 1790-MiniSymp) .  Studies of cloned ion channels expressed in heterologous cells are aimed at understanding the structural basis for ion channel function.  These studies are complemented by work in native cells from mice genetically modified to express GFP in specific cell populations.  On going studies utilize patch-clamp recording in combination with Ca2+ imaging and UV uncaging.  The ideal candidate will have 3-5 years experience with patch-clamp recording, familiarity with molecular methods and a strong record of research accomplishments.  The lab is located in the picturesque University Park Campus of the University of Southern California within close driving distance to beaches, mountains and cultural events.  For more information visit http://www.usc.edu/programs/neuroscience/faculty/profile.php?fid=48

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