Goin' fission....


This includes all of Forsburg's pombe papers, in reverse chronological order. Papers from Susan's graduate and undergraduate work can be found on PubMed.
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  • Aronica L, Kasparek T, Ruchman D, Marquez Y, Cipak L, Cipakova I, Anrather D, Mikolaskova B, Radtke M, Sarkar S, Pai CC, Blaikley E, Walker C, Shen KF, Schroeder R, Barta A, Forsburg SL, Humphrey TC. (2016) The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Nucl Acids Res. 29;44(4):1703-17


  • Sabatinos, S.A. and Forsburg, S. L. (2015) Managing Single-Stranded DNA during Replication Stress in Fission Yeast.Biomolecules Sep 18;5(3):2123-39.
  • Sabatinos, S.A., Ranatunga, N.S., Yuan, J.-P., Green, M.D., and Forsburg, S.L. (2015) Replication stress in early S phase generates apparent micronuclei and chromosome rearrangement in fission yeast Mol Biol Cell. 2015 Oct 1;26(19):3439-50
  • Sabatinos, S.A., and Forsburg, S.L. (2015). Measuring DNA content by flow cytometry in fission yeast Meth. Mol. Biol 1300:79-96
  • Green, M.D., Sabatinos, S.A., and Forsburg, S.L. (2015). Microscopy Techniques to Examine DNA Replication in Fission Yeast Meth. Mol. Biol 1300:13-41
  • Mastro TL, Forsburg SL. (2014) Increased Meiotic Crossovers and Reduced Genome Stability in Absence of Schizosaccharomyces pombe Rad16 (XPF). Genetics. Oct 6. pii: genetics.114.171355. [Epub ahead of print]
  • Ding L, Forsburg SL. (2014) Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage response. G3 (Bethesda). May 28;4(8):1373-84. doi: 10.1534/g3.114.011346.
  • Ding L, Laor D, Weisman R, Forsburg SL. (2014) Rapid regulation of nuclear proteins by rapamycin-induced translocation in fission yeast. Yeast. 2014 Jul;31(7):253-64. doi: 10.1002/yea.3014.
  • Peng JY, Chen YJ, Green MD, Sabatinos SA, Forsburg SL, Hsu CN. (2013) PombeX: robust cell segmentation for fission yeast transillumination images. PLoS One. 2013 Dec 6;8(12):e81434.
  • Forsburg SL (2013) The CINs of the centromere. Biochem Soc Trans. 2013 Dec;41(6):1706-11
  • Le, AH, Mastro, T.L, Forsburg SL. (2013) The C-terminus of S. pombe DDK subunit Dfp1 is required for meiosis-specific transcription and cohesin cleavage. Biol Open. 2013 Jun 11;2(7):728-38.
  • Li PC, Green MD, Forsburg SL. (2013) Mutations Disrupting Histone Methylation Have Different Effects on Replication Timing in S. pombe Centromere. PLoS One. May 1;8(5):e61464. doi: 10.1371/journal.pone.0061464.
  • Sabatinos, S.A. and Forsburg, S.L. (2013) Preserving the Replication Fork in Response to Nucleotide Starvation: Evading the Replication Fork Collapse Point. In: The Mechanisms of DNA Replication, Dr. David Stuart (Ed.), ISBN: 978-953-51-0991-4, InTech, DOI: 10.5772/51393. Open Access
  • Li PC, Petreaca RC, Jensen A, Yuan JP, Green MD, Forsburg SL. (2013), Replication fork stability is essential for the maintenance of centromere integrity in the absence of heterochromatin. Cell Rep. 2013 Mar 28;3(3):638-45.
  • Slaymaker IM, Fu Y, Toso DB, Ranatunga N, Brewster A, Forsburg SL, Zhou ZH, Chen XS. (2013) Nucleic Acids Res. 2013 Mar 1;41(5):3446-56.
  • Sabatinos, S.A., Mastro, T.L., Green, M.D., and Forsburg, S.L. (2013) Nucleoside analogues create DNA damage and drug sensitivity in fission yeast Genetics. 2013 Jan;193(1):143-57.
  • Sabatinos, S.A., Green, M.D., and Forsburg, S.L. (2012) Continued DNA synthesis in replication checkpoint mutants leads to fork collapse. Mol Cell Biol. 2012 Dec;32(24):4986-97.
  • Ding, L. and Forsburg, S.L. (2011) Schizosaccharomyces pombe MCM binding protein (MCM-BP) antagonizes MCM helicase. J. Biol. Chem. 286(38):32918-30
  • Li, P.C., Chretien, L., Cote, J., Kelly, T.J., and Forsburg. S.L. (2011). S. pombe replication protein Cdc18 (Cdc6) interacts with Swi6 (HP1) heterochromatin protein: region specific effects and replication timing in the centromere. Cell cycle 10(2): p. 323-36. PMC 3025051
  • Sabatinos, S.A., and Forsburg, S. L. (2010). Molecular Genetics of Schizosaccharomyces pombe Methods Enzymol 470:759-95
  • Singh SK, Sabatinos S, Forsburg S, Bastia D. (2010) Regulation of replication termination by Reb1 protein-mediated action at a distance. Cell 142(6):868-78.
  • Dolan, W.P., Le, A.-H., Schmidt, H., Yuan, J.P, Green, M.D., and Forsburg, S.L. (2010) Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage. Genetics 185(1):39-53 PMC20176980
  • Nugent, R.L., Johnsson, A., Fleharty, B., Gogol, M., Xue-Franzén, Y., Seidel, C., Wright, A.P., Forsburg, S.L. (2010) Expression profiling of S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation . BMC Genomics. 2010 Jan 22;11:59. PMC2823694

  • Luche, D.D., and Forsburg, S.L. (2009). Cell cycle synchrony for analysis of S. pombe DNA replication Meth. Mol. Biol 521:437-48.
  • Green, M.D., Sabatinos, S.A., and Forsburg, S.L. (2009). Microscopy Techniques to Examine DNA Replication in Fission Yeast Meth. Mol. Biol 521:463-82.
  • Sabatinos, S.A., and Forsburg, S.L. (2009). Measuring DNA content by flow cytometry in fission yeast Meth. Mol. Biol 521:449-61.
  • Gómez, E.G., Nugent, R.L., Laría, S., and Forsburg, S.L. (2008) S. pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation Genetics 179(2):757-71. PMC2429872
  • Bailis, J.M., Luche, D.D. Hunter, T., and Forsburg, S.L. (2008) MCM proteins interact with checkpoint and recombination proteins to promote S phase genome stability Mol. Cell. Biol. 28:1724-38. PMC2258774
  • Forsburg, S.L. (2008) The MCM helicase: at the interface of checkpoints and the replication fork. Bioch. Society Trans. 36:114-9.
  • Siam, R., Gómez, E.B., and Forsburg, S.L. (2007) S.pombe Rad4/Cut5 protein modification and chromatin association changes in DNA damage. DNA Cell Biol. 26:565-75.
  • Bailis, J.M and Forsburg, S.L. (2006). S. pombe DNA replication: pathways to cancer. In: Yeast as a Tool in Cancer Research, J. Nitiss and J. Heitman, eds. Dordrecht: Kluwer. pp. 1-35
  • Tabancay, A.P. and Forsburg, S. L. (2006). Eukaryotic DNA replication in the context of chromatin. Curr. Top. Dev. Bio. 76:129-184
  • Forsburg, S.L. and Rhind, N. (2006) Basic methods for fission yeast. Yeast, 23:173-183
  • Forsburg, S.L. (2005) The yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: models for cell biology research. Gravit. Space Biol. Bull. 18:3-9
  • Huang, H.-K., Bailis, J.M., Leverson, J.D., Gómez, E.B., Forsburg, S.L. and Hunter, T. (2005) The chromosomal passenger protein Bir1p (Survivin) interacts with Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation. Mol. Cell Biol. 25:9000-15. PMC1265766
  • Gómez, E.B, Espinosa, J., and Forsburg, S.L. (2005) S. pombe mst2+ encodes a MYST-family histone acetyltransferase that negatively regulates telomere silencing. Mol. Cell Biol. 25:8887-903.. PMC1265769
  • Pankratz, D.G., and Forsburg, S.L. (2005) Meiotic S-phase damage activates recombination without check¬point arrest . Mol. Biol. Cell16:1651-1660. PMC1073649
  • Freeman-Cook, L L., Gómez, E.B., Spedale, E.J., Marlett, J., Forsburg, S.L., Pillus, L., and Laurenson, P. (2005) Conserved locus-specific silencing functions of S. pombe sir2+. Genetics169(3):1243-1260. PMC1449530
  • Sandler J., Forsburg, S.L., and Faulkner, J. (2005) Bioactive steroidal glycosides from the marine sponge Erylus lendenfeldi . Tetrahedron 61:1199-1206
  • Gómez, E.B., Angeles, V.T., and Forsburg, S.L. (2005) A novel screen for S. pombe replication mutants identifies new alleles of cut9+, rad4+, and psf2+. Genetics 169:77-89. PMC1448876

  • Forsburg, S.L. (2004). Cell Cycle: Control of Entry and Progression through S phase. In: Encyclopedia of Biological Chemistry, W. Lennarz and M.D. Lane, eds. Oxford: Elsevier. Vol 1, pp.332-337
  • Siam, R., Dolan, W.P., and Forsburg, S.L. (2004) Choosing and using S. pombe plasmids. Methods 33:189-198.
  • Bailis, J. M. and Forsburg, S. L. (2004). S phase assembly of centromeric heterochromatin and cohe¬sion. Cell Cycle 3:416-418
  • Forsburg, S.L. (2004). Eukaryotic MCM proteins: beyond replication initiation. Mol. Micro. Biol. Rev. 68:109-131 .. PMC362110
  • Bailis, J.M. and Forsburg, S.L. (2004). MCM proteins: DNA damage, mutagenesis, and repair. Curr. Op. Gen. Dev. 14 :17-21
  • Gómez, E.B., and Forsburg, S.L. (2004) Analysis of Schizosaccharomyces pombe cell cycle. Methods Mol. Biol. 241 pp. 93-111
  • Dolan, W.P., Sherman, D.A., and Forsburg, S.L. (2004) S. pombe replication protein Cdc45/Sna41 requires Hsk1/Cdc7 and Rad4/Cut5 for chromatin binding. Chromosoma 113:145-156
  • Forsburg, S. L. 2003. Introduction of DNA into S. pombe cells. Curr Protoc Mol Biol Unit 13 17.
  • Forsburg, S. L. 2003. Growth and manipulation of S. pombe. Curr Protoc Mol Biol Unit 13 16.
  • Forsburg, S. L. 2003. S. pombe strain maintenance and media. Curr Protoc Mol Biol Unit 13 15.
  • Forsburg, S. L. 2003. Overview of Schizosaccharomyces pombe. Curr Protoc Mol Biol Unit 13-14.
  • Bailis, J.M. and Forsburg, S.L. (2003). It's all in the timing: linking S phase to chromatin structure and chromosome dynamics. Cell Cycle 2:303-306
  • Bailis, J.M., Bernard, P., Antonelli, R., Allshire, R., and Forsburg, S.L. (2003) Hsk1-Dfp1 is required for heterochromatin mediated cohesion at centromeres. Nat. Cell Biol. 5:1111-1116 (cover).
  • Hodson, J.A., Bailis, J.M. and Forsburg, S.L. (2003) Efficient labeling of fission yeast S. pombe by thymidine and BUdR. Nucl. Acids Res. 31:e134. PMC275491
  • Catlett, M.G. and Forsburg, S.L. (2003). S. pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double strand breaks. Mol. Biol. Cell 14:4707-4720 w/ video online.. PMC266785
  • Snaith, H.A., Marlett, J., and Forsburg, S.L. (2003) Overproduction of Ibp1p, a novel Cdc25-related phosphatase, suppresses S. pombe hsk1 (cdc7). Curr.Genet. 44: 38-48
  • Bailis, J.M. and Forsburg, S.L. (2002). RNAi hushes the heterochromatin. Genome Biology 3:1035.1-1035.4. PMC151193
  • Gómez, E.B., Bailis, J.M., and Forsburg, S.L. (2002) Fission yeast enters a joyful new era. Genome Biology 3:4017.1-4017.3. PMC139370
  • Forsburg, S. L. (2002). Only connect: linking meiotic S phase to downstream events. Mol. Cell. 9:703-11
  • Gómez, E.B., Catlett, M.G., and Forsburg, S.L. (2002) Different in vivo phenotypes associated with ATPase motif mutations of S. pombe MCM proteins. Genetics, 160:1305-1318. PMC1462049
  • Leverson, J.D, Huang, H.-K., Forsburg, S.L. and Hunter, T. (2002) The Schizosaccharomyces pombe Aurora-Related Kinase (Ark1) interacts with the Inner Centromere Protein (INCENP) Pic1, and mediates chromosome segregation and cytokinesis. Mol. Biol. Cell 13:1132-1143. PMC102257
  • Wood, V., Gwilliam, R., Rajandream, M., Lyne, M., Lyne, R., et al. (2002). The genome sequence of the eukaryote fission yeast Schizosaccharomyces pombe. Nature 415:871-880
  • Forsburg, S.L. (2001). Fission Yeast. In: 2002 Yearbook of Science and Technology. New York: McGraw Hill. pp. 108-110
  • Forsburg, S. L. (2001) The art and design of genetic screens: yeast. Nat. Rev. Genet. 2:659-68
  • Pasion, S.G. and Forsburg, S.L. (2001). Deconstructing a conserved protein family: the role of MCM proteins in eukaryotic DNA replication. In: Genetic Engineering, Principles and Methods, vol. 23 J. K. Setlow, ed. New York: Plenum Press. pp. 129-156
  • Forsburg, S.L. (2001). Yeast Plasmids. In: Encyclopedia of Genetics, S. Brenner and J. Miller, eds. Academic Press London. pp. 2162-2164
  • Huang, H.-K., Forsburg, S. L., John, U.P., O’Connell, M.J., and Hunter, T. (2001). Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe. J. Cell Sci. 114:3779-3788
  • Liang, D.T., and Forsburg, S.L. (2001). Characterization of S. pombe mcm7+ and cdc23+ (MCM10) and interactions with replication checkpoints Genetics 159: 471-486. PMC1461838
  • Forsburg, S.L. (2000). Themes and Variations: The Salk Cell Cycle Meeting. BBA (Reviews on Cancer) 1470: 13-16
  • Pasion, S.G., Gómez, E.B., and Forsburg, S.L. (2000) Dynamic chromosomes. Genome Biology 1:4020.1-4020.3. PMC138880
  • Snaith, H.A., Brown, G., and Forsburg, S.L. (2000) S. pombe Hsk1p is a potential Cds1p target required for genome integrity. Mol. Cell. Biol. 20:7922-7932. PMC86403
  • Forsburg, S.L. and Hodson, J.A. (2000) Mitotic replication initiation proteins are not required for S. pombe pre-meiotic S phase. Nat. Genet. 25:263-268
  • Bishop, D.T., Macdonald, H., Gould, K.L., and Forsburg, S.L. (2000) Isolation of an essential S. pombe gene, prp31+, linking splicing and meiosis. Nucl Acids Res. 28: 2214-2220. PMC102626

  • Forsburg, S.L. (1999). The Best Yeast? Trends Genet. 15:340-344
  • Pasion, S.G. and Forsburg, S.L. (1999) Nuclear localization of fission yeast Mcm2/Cdc19p requires MCM complex formation. Mol Biol. Cell 10: 4043-4057. PMC25742
  • Snaith, H.A. and Forsburg, S.L. (1999) Re-replication in fission yeast requires MCM proteins and other S phase genes. Genetics 152: 839-851. PMC1460649
  • Liang, D.T., Hodson, J.A. and Forsburg, S.L. (1999) Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay. J. Cell Sci. 112:559-567
  • Sherman, D. A. and Forsburg, S. L. (1998). S. pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p). Nucl. Acids Res. 26:3955-3961. PMC147805
  • Sherman, D.A., Pasion, S.G., and Forsburg, S.L. (1998) Multiple domains of fission yeast Cdc19p (MCM2) are required for association with the core MCM complex. Mol. Biol. Cell 9:1833-1845. PMC25423
  • Gould, K.L. , Burns, C.G., Feoktistova, A., Hu, C.-P., Pasion, S.G., and Forsburg, S.L. (1998). Fission yeast cdc24+ encodes a novel replication factor required for chromosome integrity. Genetics 149:1221-1233. PMC1460225
  • Bezanilla, M., Forsburg, S.L., and Pollard, T.D. (1997) Identification of a second conventional myosin in S. pombe: Myp2p is conditionally required for cytokinesis. Mol. Biol. Cell 8: 2693-2705. PMC25737
  • Forsburg, S.L., Sherman, D.A., Ottilie, S., Yasuda, J.R., and Hodson, J.A. (1997). Mutational analysis of the S. pombe Cdc19p DNA replication protein. Genetics 147: 1025-1041. PMC1208231
  • Forsburg, S.L., and Sherman, D.A. (1997). General purpose tagging vectors for fission yeast. Gene 191: 191-195
  • Forsburg, S.L. (1996). Regulation of S phase in the yeast S. pombe. In: Eukaryotic DNA Replication, J.J. Blow, ed. Oxford: Oxford University Press pp197-228
  • Ottilie, S., Miller, P.J., Johnson, D.I., Creasy, C.L., Sells, M.A., Bagrodia, S., Forsburg, S.L., and Chernoff, J. (1995). Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is in¬volved in the control of cell polarity. EMBO J. 14:5908-5919. PMC394709
  • Forsburg, S.L. and Nurse, P. (1994). The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins. J. Cell Sci. 107:2779-2788
  • Forsburg, S.L. (1994). Codon usage table for Schizosaccharomyces pombe. Yeast 10: 1045-1047
  • Forsburg, S.L. and Nurse, P. (1994). Analysis of the S. pombe cyclin puc1: evidence for a role in cell cycle exit. J. Cell Sci. 107: 601-613
  • Forsburg, S.L. (1994). In and out of the cell cycle. Current Biology 4: 828-830