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Research
Areas
of Interest
BioMEMS, microfluidics,
lab-on-a-chip, microsystem integration and packaging, world-to-chip
interfacing, cell-to-chip interfacing, implantable biomedical
microdevices
Research
The focus of the Biomedical Microsystems
Laboratory is to leverage micro- and nano-technologies to develop drug
delivery platforms that achieve three main goals: (1) benchtop tools
compatible with both dissociated cells and whole tissue for rapid
scientific and drug discovery, (2) implants intended for animal models
of diseases for targeted release, and (3) translational medical device
technologies for the treatment of human conditions.
The ability to delivery or extract minuscule
volumes of fluid with spatiotemporal precision is an extremely powerful
technology that enables advanced biomedical therapies. These
technologies advance beyond conventional needles for drug injection or
Petri-dish based biomedical research. This approach may lead to
effective treatments of central nervous system injuries (e.g. traumatic
brain injury, spinal cord injury, and stroke), epilepsy, cancer, and
other diseases that result in devastating lifelong physical disabilities
in millions of Americans. Many of these conditions are presently
incurable and drug therapy is the preferred treatment method. My
research team is engaged in several clinical collaborations to address
these conditions and is even looking at ways to better understand drug
addiction with our devices. Furthermore, we are developing next
generation closed-loop drug delivery platforms that include integrated
sensors that can detect when drug is needed, trigger the delivery, and
continually monitor the effectiveness of the treatment.
For details on specific research areas,
please visit the lab webpage (click link on the right).
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